Transfusion-transmitted Babesia spp.: a changing landscape of epidemiology, regulation, and risk mitigation

Author:

Drews, SJ, Kjemtrup, A, Krause, PJ, Lambert, G, Leiby, DA, Lewin, A, O'Brien, SF, Renaud, C, Tonnetti, L, and Bloch, EM

Publication type:

Journal Article

Publication date:

2023-09

Journal/Series title:

J Clin Microbiol

Volume:

Sep 26

URL:

https://journals.asm.org/doi/10.1128/jcm.01268-22?url_ver=Z39.88-2003&rfr_id=ori...

Abstract:

In this review, we provide an overview of the clinical presentation and epidemiology of TTB. We identify approaches and technologies to reduce the risk of collecting blood products from Babesia-infected donors and describe how investigations of TTB are undertaken. We also describe how microbiologists in Babesia non-endemic regions can assess for changing risks of TTB and decide when to focus on laboratory-test-based approaches or pathogen reduction to reduce TTB risk.