Human Complement Evasion Is Widespread Among Lyme Borreliosis Spirochete Species

Author:

Golovchenko, M, Kratzerova, L, MacTavish, H, Lloyd, V, and Rudenko, N

Publication type:

Journal Article

Publication date:

2026-07

Journal/Series title:

Pathogens

Volume:

Issue:

URL:

https://www.mdpi.com/2076-0817/15/7/717

Abstract:

Our findings suggest that the ability to evade human complement may be more widespread among Borrelia species than previously assumed. These results support an emerging model in which complement-mediated selection may shape host associations and transmission success without serving as an absolute predictor of Borrelia virulence.