An update and review of arthropod vector sensory systems: Potential targets for behavioural manipulation by parasites and other disease agents

Author:

Doherty, JF, Ames, T, Brewster, LI, Chiang, J, Cyr, E, Kelsey, CR, Lee, JP, Liu, B, Lo, IHY, Nirwal, GK, Mohammed, YG, Phelan, O, Seyfourian, P, Shannon, DM, Tochor, NK, and Matthews, BJ

Publication type:

Journal Article

Publication date:

2024-03

Journal/Series title:

Adv Parasitol

Volume:

124

URL:

https://www.sciencedirect.com/science/article/abs/pii/S0065308X24000046?via%3Dih...

Abstract:

An important yet overlooked component of arthropod vector ecology are the phenotypic changes observed in infected vectors that increase disease transmission. While our fundamental understanding of sensory mechanisms in disease vectors has drastically increased due to recent advances in genome engineering, for example, the advent of CRISPR-Cas9, and high-throughput "big data" approaches (genomics, proteomics, transcriptomics, etc.), we still do not know if and how parasites manipulate vector behaviour. Here, we review the latest research on arthropod vector sensory systems and propose key mechanisms that disease agents may alter to increase transmission.