Modified Two-Tiered Testing Enzyme Immunoassay Algorithm for Serologic Diagnosis of Lyme Disease
| Title | Modified Two-Tiered Testing Enzyme Immunoassay Algorithm for Serologic Diagnosis of Lyme Disease |
| Publication Type | Journal Article |
| Year of Publication | 2022 |
| Journal | Open Forum Infect Dis |
| Volume | 9 |
| Issue | 7 |
| Start Page | ofac272 |
| Date Published | 06/2022 |
| Authors | Khan FM, Allehebi ZO, Shabi Y, Davis IRC, LeBlanc J, Lindsay LR, Hatchette TF |
| Keywords | borrelia burgdorferi, diagnostics, Lyme disease, modified two-tiered testing, serology |
| Abstract | The modified 2-tier testing algorithm (MTTT) for Lyme disease (LD) has been approved by the US Food and Drug Administration. In this study, we show that the MTTT detected 28% more cases of early infection compared with the standard 2-tier algorithm while retaining high specificity in a region with a high incidence of LD. |
| URL | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297310/ |
