Neurosyphilis and Lyme neuroborreliosis

TitleNeurosyphilis and Lyme neuroborreliosis
Publication TypeJournal Article
Year of Publication2021
AuthorsDersch R, Singh AE
JournalCurr Opin Neurol
Date Published03/2021
KeywordsLyme disease, Lyme neuroborreliosis, neurosyphilis, review

The diagnosis of NS may be delayed due to a lack of specificity of findings, low suspicion for syphilis, and/or similarities in presentation to other diseases. A high index of suspicion for syphilis is required provide timely diagnosis and management of NS. Fortunately, penicillin remains the treatment of choice. Overdiagnosis and overtreatment in patients labelled as having Lyme disease can be avoided by an evidence-based approach towards diagnosis and treatment.