Analysis of an Ordered, Comprehensive STM Mutant Library in Infectious Borrelia burgdorferi: Insights into the Genes Required for Mouse Infectivity.
| Title | Analysis of an Ordered, Comprehensive STM Mutant Library in Infectious Borrelia burgdorferi: Insights into the Genes Required for Mouse Infectivity. |
| Publication Type | Journal Article |
| Year of Publication | 2012 |
| Journal | PLoS ONE |
| Volume | 7 |
| Issue | 10 |
| Start Page | e47532 |
| Date Published | 10/2012 |
| Authors | Lin T, Gao L, Zhang C, Odeh E, Jacobs MB, Coutte L, Chaconas G, Philipp MT, Norris SJ |
| Keywords | biology, borrelia, burgdorferi, geens |
| Abstract | Using the infectious, moderately transformable B. burgdorferi derivative 5A18NP1 and signature-tagged versions of the Himar1 transposon vector pGKT, we have constructed a defined transposon library for the efficient genome-wide investigation of genes required for wild-type pathogenesis, in vitro growth, physiology, morphology, and plasmid replication. |
| URL | http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0047532 |
| DOI | 10.1371/journal.pone.0047532 |
