Disseminated Lyme disease and dilated cardiomyopathy: A systematic review

TitleDisseminated Lyme disease and dilated cardiomyopathy: A systematic review
Publication TypeJournal Article
Year of Publication2022
JournalTrends Cardiovasc Med
Date Published06/2022
AuthorsMotamed M, Liblik K, Miranda-Arboleda AF, Wamboldt R, Wang CN, Cingolani O, Rebman AW, Novak CB, Aucott JN, Farina JM, Baranchuk A
Keywordsborrelia burgdorferi, carditis, Dilated cardiomyopathy, Lyme disease
Abstract

Lyme carditis is a well-established manifestation of early disseminated Lyme infection, yet the relationship between late disseminated Lyme disease and the development of dilated cardiomyopathy (DCM) remains unclear. The present systematic review aims to summarize existing literature on the association between late disseminated Lyme disease and DCM. A systematic review was conducted in PubMed, Embase, CENTRAL, and MEDLINE databases, after which a total of 11 observational studies (n = 771) were ultimately included for final data extraction. Although most studies (7/11) identified evidence associating Borrelia-infection with DCM, further research is required to isolate late disseminated Borrelia infection as a causative agent of DCM.

URLhttps://www.sciencedirect.com/science/article/abs/pii/S1050173822000779?via%3Dihub