Comparative genomic analysis of Babesia duncani responsible for human babesiosis

TitleComparative genomic analysis of Babesia duncani responsible for human babesiosis
Publication TypeJournal Article
Year of Publication2022
JournalBMC Biol.
Volume20
Issue1
Start Page153
Date Published07/2022
AuthorsWang J, K, C, Yang J, Zhang S, Li Y, Liu G, Luo J, Yin H, Wang G, Guan G
Abstract

Using ONT sequencing and Illumina sequencing technologies, we provide the first B. duncani reference genome and confirm that B. duncani forms a phylogenetically distinct clade from other Piroplasm parasites. Comparative genomic analyses show that two gene families are significantly expanded in B. duncani and may play important roles in host cell invasion and virulence of B. duncani. Our study provides basic information for further exploring B. duncani features, such as host-parasite and tick-parasite interactions.

URLhttps://bmcbiol.biomedcentral.com/articles/10.1186/s12915-022-01361-9