Susceptibility to infection with Borrelia afzelii and TLR2 polymorphism in a wild reservoir host

TitleSusceptibility to infection with Borrelia afzelii and TLR2 polymorphism in a wild reservoir host
Publication TypeJournal Article
Year of Publication2019
AuthorsGomez-Chamorro, A, Battilotti, F, Cayol, C, Mappes, T, Koskela, E, Boulanger, N, Genne, D, Sarr, A, Voordouw M
JournalSci Rep
Volume9
Issue1
Date Published04/2019
Abstract

The study of polymorphic immune genes in host populations is critical for understanding genetic variation in susceptibility to pathogens. Controlled infection experiments are necessary to separate variation in the probability of exposure from genetic variation in susceptibility to infection, but such experiments are rare for wild vertebrate reservoir hosts and their zoonotic pathogens.

URLhttps://www.ncbi.nlm.nih.gov/pubmed/31040326