Metabolites of prostaglandin synthases as potential biomarkers of Lyme disease severity and symptom resolution

TitleMetabolites of prostaglandin synthases as potential biomarkers of Lyme disease severity and symptom resolution
Publication TypeJournal Article
Year of Publication2019
AuthorsJarosz, AC, Badawi A
JournalInflamm Res.
Volume68
Issue1
Date Published01/2019
Abstract

Lyme disease or Lyme borreliosis (LB) is the commonest vector-borne disease in the North America. It is an inflammatory disease caused by the bacterium Borrelia burgdorferi. The role of the inflammatory processes mediated by prostaglandins (PGs), thromboxanes and leukotrienes (LTs) in LB severity and symptoms resolution is yet to be elucidated. We aim to systematically review and evaluate the role of PGs and related lipid mediators in the induction and resolution of inflammation in LB.

URLhttps://www.ncbi.nlm.nih.gov/pubmed/30121835