|Title||Metabolites of prostaglandin synthases as potential biomarkers of Lyme disease severity and symptom resolution|
|Publication Type||Journal Article|
|Year of Publication||2019|
|Authors||Jarosz AC, Badawi A|
Lyme disease or Lyme borreliosis (LB) is the commonest vector-borne disease in the North America. It is an inflammatory disease caused by the bacterium Borrelia burgdorferi. The role of the inflammatory processes mediated by prostaglandins (PGs), thromboxanes and leukotrienes (LTs) in LB severity and symptoms resolution is yet to be elucidated. We aim to systematically review and evaluate the role of PGs and related lipid mediators in the induction and resolution of inflammation in LB.