Lyme neuroborreliosis presenting as spinal myoclonus

TitleLyme neuroborreliosis presenting as spinal myoclonus
Publication TypeJournal Article
Year of Publication2019
AuthorsLi X, Kirschner A, Metrie M, Loeb M
JournalBMJ Case Rep
Date Published12/2019
KeywordsBorrelia afzelli, infection (neurology), infections, Lyme disease, neurology (drugs and medicines)

Early neurological Lyme disease (neuroborreliosis) typically presents with well-recognised neurological syndromes. Spinal myoclonus is however a rare manifestation of neuroborreliosis. We present the case of a man who developed spinal myoclonus 3 weeks after returning from the Czech Republic where he developed erythema migrans on his arm following multiple tick exposures. Spinal fluid analysis showed a pleocytosis and MRI showed enhancement at C5-C6. His serology was positive for IgM antibodies to Borrelia afzelli He was successfully treated with ceftriaxone and doxycycline with improvement of his spinal myoclonus and radiculitis. We conclude that early Lyme neuroborreliosis may present with uncommon neurological manifestations and so a high degree of suspicion is needed.