Lyme borreliosis as a trigger for NMDA receptor encephalitis?

TitleLyme borreliosis as a trigger for NMDA receptor encephalitis?
Publication TypeJournal Article
Year of Publication2018
AuthorsMartinez HR, Olguin-Ramirez LA, Camara-Lemarroy CR
JournalNeurol Sci
Volume39
Issue10
Date Published10/2018
Abstract

NMDA receptor (NMDAR) encephalitis was initially described by Dalmau et al. [1] and is associated to a constellation of symptoms such as psychosis, memory deficits, seizures, abnormal movements, and autonomic dysfunction. In many patients, these autoantibodies occur in the setting of underlying tumor (teratomas), but in the remainder of patients, the immunopathogenesis remains unclear. Recent reports suggest that viral infections may trigger NMDAR [2], leading to speculation that mechanisms such as molecular mimicry and/or bystander activation may play a role.

URLhttps://link.springer.com/article/10.1007%2Fs10072-018-3497-9