Suggested Role for G4 DNA in Recombination Switching at the Antigenic Variation Locus of the Lyme Disease Spirochete.

TitleSuggested Role for G4 DNA in Recombination Switching at the Antigenic Variation Locus of the Lyme Disease Spirochete.
Publication TypeJournal Article
Year of Publication2013
AuthorsWalia R, Chaconas G
JournalPLoS ONE
Volume8
Start Pagee57792
Issue2
Date Published02/2013
Keywordsantigenic, bacteria, biology, lyme, spirochete, variation
Abstract

In the work presented here we show that G4 DNA can be formed by sequences within the B31 vlsE locus, prompting us to investigate the presence of potential G4-forming DNA throughout the vls locus of several Lyme spirochete strains and species.

URLhttp://www.plosone.org/article/info:doi/10.1371/journal.pone.0057792
DOI10.1371/journal.pone.0057792